Projects Overview
Current Projects
DARPA, NTRAIN: Normalizing Timing of Rhythms Across Internal Networks of Circadian Clocks
Hybrid Bioelectronic/Cell Therapy Device $36M
This multi-institute collaborative project focuses on engineering an implantable device for metabolic regulation with a focus on entrainment of the circadian system. The device consists of engineered cells that release entrainment factors, and these cells are controlled by an electronic system co-contained in the device.
DARPA, REPAIR: Regenerative Electronic Platform through Advanced Intelligent Regulation
Hybrid Bioelectronic/Cell Therapy Device $22M
This multi-institute collaborative project focuses on engineering a topical device for accelerating wound healing. The device consists of engineered cells that secrete wound healing factors, electrical stimulators, and sensors that are all controlled by an on-device microcontroller.
Gates Foundation: Cell Factories for Durable Protein Expression
Cell Therapy $3M
This project focuses on engineering a cell-based therapy for stopping HIV in a setting with low medication adherence. This consists of engineering cells to continually secrete antibodies over an extended period of time that can neutralize HIV.
ARPA-H, THOR: Targeted Hybrid Oncotherapeutic Regulation
Hybrid Bioelectronic/Cell Therapy Device $45M
This multi-institute collaborative project focuses on engineering an implantable device for accelerating treating cancer. The device consists of engineered cells that secrete cancer immunotherapies and sensors that sense efficacy and toxicity biomarkers.
